Rate-Distortion Modeling for Bit Rate Constrained Point Cloud Compression

As being one of the main representation formats of 3D real world and well-suited for virtual reality and augmented reality applications, point clouds have gained a lot of popularity. In order to reduce the huge amount of data, a considerable amount of research on point cloud compression has been done. However, given a target bit rate, how to properly choose the color and geometry quantization parameters for compressing point clouds is still an open issue. In this paper, we propose a rate-distortion model based quantization parameter selection scheme for bit rate constrained point cloud compression. Firstly, to overcome the measurement uncertainty in evaluating the distortion of the point clouds, we propose a unified model to combine the geometry distortion and color distortion. In this model, we take into account the correlation between geometry and color variables of point clouds and derive a dimensionless quantity to represent the overall quality degradation. Then, we derive the relationships of overall distortion and bit rate with the quantization parameters. Finally, we formulate the bit rate constrained point cloud compression as a constrained minimization problem using the derived polynomial models and deduce the solution via an iterative numerical method. Experimental results show that the proposed algorithm can achieve optimal decoded point cloud quality at various target bit rates, and substantially outperform the video-rate-distortion model based point cloud compression scheme.Comment: Accepted to IEEE Transactions on Circuits and Systems for Video Technolog

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field

Intuitive transfer function editing using relative visibility histograms

In this paper, we present an interactive approach for intuitively editing colors and opacity values in transfer functions for volume visualization. We introduce the concept of a relative visibility histogram, which represents the difference between the global visibility distribution across the full volume and the local visibility distribution within a user-selected region in the viewport. From this measure, we can infer what subset of the 3D volume the user intends to select when they click on a region in the 2D rendered image of the data set, and use this to modify relevant parts of the transfer function. We use this selection mechanism for two alternative purposes. The first is to allow output-driven editing of the transfer function, whereby a user can change the opacity values and colors of features without directly having to manipulate the transfer function itself. The second is to extract visually dominant features in any user-selected region of interest, so that the user may individually edit their appearance and then merge these to create new transfer functions. Our approach is lightweight compared to similar techniques and performs in real-time

Intuitive transfer function editing using relative visibility histograms

In this paper, we present an interactive approach for intuitively editing colors and opacity values in transfer functions for volume visualization. We introduce the concept of a relative visibility histogram, which represents the difference between the global visibility distribution across the full volume and the local visibility distribution within a user-selected region in the viewport. From this measure, we can infer what subset of the 3D volume the user intends to select when they click on a region in the 2D rendered image of the data set, and use this to modify relevant parts of the transfer function. We use this selection mechanism for two alternative purposes. The first is to allow output-driven editing of the transfer function, whereby a user can change the opacity values and colors of features without directly having to manipulate the transfer function itself. The second is to extract visually dominant features in any user-selected region of interest, so that the user may individually edit their appearance and then merge these to create new transfer functions. Our approach is lightweight compared to similar techniques and performs in real-time

Effects of aeration rate on maturity and gaseous emissions during sewage sludge composting

This study investigated effects of aeration rate (AR) on maturity and gaseous emissions during sewage sludge composting, sewage sludge and corn stalks as the bulking agent were co-composted at different ARs (0.1, 0.2, 0.3 L·kg−1 dry matter (DM)·min−1). The thermophilic phase for the low and moderate AR treatments was able meet sanitation requirements, but too short to meet sanitation requirements in the high AR treatment. The high AR treatment was significantly different from the other treatments, and had the lowest electrical conductivity and highest E4/E6(absorbance ratio of wavelength 465 and 665 nm). The AR influences the nitrogen variations; high AR compost had the highest NH4+-N content and lowest NOx−-N content. The AR was the main factor influencing compost stability, but the AR had little impact on pH and the germination index. The moderate AR treatment had the highest NH3 emissions during composting, while the low AR treatment had the highest CH4 and N2O emissions. Based on our comprehensive investigation, the recommended AR for sludge composting is 0.2 L·kg−1 DM·min−1

Preferential CO oxidation (CO-PROX) catalyzed by CuO supported on nanocrystalline CeO2 prepared by a freeze-drying method

CuO supported on CeO2, Ce0.8Zr0.2O2 and Ce0.8Al0.2O2 based catalysts with 6 wt.% of copper were synthesized and tested in the preferential oxidation of CO in a H2-rich stream (CO-PROX). Three nanocrystalline supports, CeO2 and solid solutions of modified CeO2 with zirconium and aluminium were prepared by a freeze-drying method. CuO was supported by incipient wetness impregnation and calcination at 400 ºC. All the prepared catalysts resulted active in the CO-PROX reaction and selective to CO2 at low reaction temperature, being the catalyst supported on CeO2 the more active and stable. The influence of the presence of CO2 and H2O was also studied

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field